The authors Kettles present a stereotypical case presentation of X-linked hypophosphatemia (XLH) and provide a review of the pathophysiology and related pharmacology of this condition, primarily focusing on the FDA-approved medication burosumab.XLH is a renal phosphate wasting disorder caused by loss of function mutations in the PHEX gene (phosphat
"nImam Khomeini Relief Foundation (IKRF) was officially established on March 5th 1979, to aid the underprivileged, allevi­ate poverty and improve the self sufficiency of Folding Hunting the needy people.The Foundation, funded mainly by people's contributions, has implemented several plans to preserve human benevolence, assist the
A new digamasellid mite, Longoseius (Longoseiulus) disparisetus sp.nov., was described from females found in the wood detritus of tree cavity of freshly felled elm (Fraxinus sp.) in a park in southwestern Slovakia.The new species differs from known congeners by the number of setae on some leg segments (genu II with eight setae, tibiae II and III wi
The geographically dispersed resources and ever-changing context incur unique heterogeneity, potential fragility, and vulnerability of an edge-cloud system.Thus, the reliability guarantee of services in the edge-cloud is critical.This paper firstly proposes a QoS-aware scheduling model with fault-tolerance in the edge-cloud, which extends the tradi
Abstract Background Appropriate flowering time is very important to the success of modern agriculture.Maize (Zea mays L.) is a major cereal crop, originated in tropical areas, with photoperiod sensitivity.Which is an important obstacle to the utilization of tropical/subtropical germplasm resources in temperate regions.However, the study on the regu